The focus of our research is to develop integrated, automated and high-throughput microfluidic and Lab-on-a-Chip (LoC) devices for medical, biological, and environmental applications. We are interested in all aspects of these miniaturized devices, from design of functional materials, to development of compatible microfabrication techniques for their integration into LoC devices in the form of microstructures, to application of such devices in organism-on-a-chip assays or point-of-care and point-of-need diagnosis and detection of various analytes and biomarkers.


FUNCTIONAL MATERIALS AND MICROSTRUCTURES IN MINIATURIZED DEVICES

Composite Polymer Bridges

PDMS and Ag-PDMS Micropillars and Microbridges

We aim to develop composite polymers with functional properties (e.g., electrical, thermal, optical) for sensing and actuation purposes and integrate them into miniaturized microfluidic devices in the form of 3D microstructures using novel microfabrication techniques.

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APPLICATIONS OF MINIATURIZED DEVICES

Organisms-on-a-Chip
Microfluidic 1

Drosophila melanogaster (left) and Caenorhabditis elegans (right) Multidirectional Manipulation on a Chip

We investigate Lab on a Chip and miniaturized devices that provide higher precision and control for studying model organisms (e.g. C. elegans, Drosophila, and zebrafish) responses to various environmental cues (e.g. mechanical, thermal, electrical and chemical). Our goal is to develop high throughput chemical screening devices for drug discovery applications.

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Microparticles and Microorganisms Sorting and Separation
Magnetic sorter 1

Magneto-Hydrodynamic Sorter Device

We conduct research on microfluidic devices to perform sample (e.g. water, blood, saliva, urine) processing from preparation and sorting to detection of microorganisms and microparticles in a rapid, precise and automated manner. Our goal is to enhance the throughput of such devices and achieve multiplexed sorting with high purity for applications in environmental safety and Point of Care (POC) diagnosis.

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